"Targeted antioxidant approach may be the elusive additive therapy"

Oxidative stress as a major culprit in kidney disease in diabetes.
[Journal Article, Research Support, N.I.H., Extramural, Research
Support, Non-U.S. Gov't]
Forbes JM, Coughlan MT, Cooper ME
Diabetes 2008 Jun; 57(6):1446-54.

It is postulated that localized tissue oxidative stress is a key
component in the development of diabetic nephropathy. There remains
controversy, however, as to whether this is an early link between
hyperglycemia...