That would explain why interferon works .. so .. well .. ?
May explain the poor birth rates too.
http://doctor.medscape.com/viewarticle/496544
Interferon alfa is effective in suppressing bone marrow function in
chronic myeloproliferative disorders, but this treatment requires
multiple weekly injections.
"The complication rate was 67%% in untreated pregnancies vs none in
aspirin- or interferon-treated women"
Finally, one group of investigators reviewed their experience with 40
pregnancies in 16 women with essential thrombocytosis. There was no
difference in platelet counts in those pregnancies resulting in fetal
loss vs those resulting in a live birth. Spontaneous abortion during
the first trimester was the most common complication, occurring in 33%%
of patients. Overall, the complication rate was 67%% in untreated
pregnancies (18/27) vs none in aspirin- or interferon-treated women
(0/13).[38]
These data indicate that idiopathic erythrocytosis is not rare and
that phlebotomy alone is both necessary and sufficient to prevent
thrombosis in such patients.