Hmm, it doesn't sound that it is illegal from these factbites I am
pulling up. The exact, and patented chemical formula I am taking is
different than pure straight methoxy apparently. but here is what I
pulled up. Still, I think I may return it because of certain
similarities I am noticing, depending on how I feel when the drug wears
off.

Methoxyisoflavone
Nonessential Micronutrient

OVERVIEW

Summary
Livestock producers around the world are using an isoflavone (a plant
chemical with "steroid-like" effects) called methoxy to naturally
increase the size of their animals (hormone free), so there's probably
some potential here. Despite the claims, though, there's just not
enough evidence to show that it has any real potential for enhancing
muscle size in humans. There are other more effective isoflavones, like
ipriflavone (daidzein), the one methoxy's claims are based on, which
supports both your skeletal system and heart.

Other names for Methoxyisoflavone
5-methyl-7-methoxy-isoflavone, 7 methoxy, ipriflavone, methoxyflavone,
methoxy

Proprietary Information
U.S. patent 4,163,746 (filed in 1977, and now expired).

Where to find Methoxyisoflavone
Methoxyflavone is a synthetic extract - a version of one of the major
isoflavones, which are plant-based compounds with estrogen-like effects
found primarily in soybeans.

PERFORMANCE BENEFITS

Why athletes use Methoxyisoflavone
The claims of methoxy's muscle-building potential are fairly
exaggerated and clearly lack supporting science. Although it's been
shown and used for decades to increase the weight of barnyard animals,
that doesn't necessarily mean it works or is safe for us too. On the
other hand, the isoflavone upon which methoxy was based, ipriflavone
(daidzein), remains as useful as ever for the skeletal system and
heart. For more information on soy isoflavones, see our nutrient
profile on soy protein.

Ways that Methoxyisoflavone can enhance Muscle Gain & Recovery:

Potentially increase muscle mass by increasing nitrogen retention
Supposedly help suppress cortisol levels and spare muscle tissue
Ways that Methoxyisoflavone can enhance Fat Loss:

Possibly decrease fat by suppressing appetite and transporting
nutrients away from fat tissue

HEALTH BENEFITS

Signs of Methoxyisoflavone deficiency
No deficiency conditions are known to exist.

Potential uses for Methoxyisoflavone
Research indicates that Methoxyisoflavone may be useful in the
treatment of:

Catabolism (muscle wasting)
Pathological thinness

DISCUSSION

More about Methoxyisoflavone
Methyl-7-methoxy-isoflavone is a slightly altered version of
ipriflavone (7-isopropoxyisoflavone), and because it's considered a
chemical cousin of this compound, it's been suggested to have similar
functions. But let's get something straight right off the top: they
aren't the same, and they don't produce the same array of benefits.
Unfortunately, what's happened as a result of this "slight"
misconception is that manufacturers have allegedly used the actual
science behind ipriflavone (a soy derivative also called daidzein) to
make methoxy seem valid and more potent than it really is. So while
ipriflavone has a more solid history of health benefits, methoxy does
not share that history - in the least. Confused yet? We were... but
now that we've scoured the research and medical journals and sorted it
all out, we've uncovered the facts.

How it all started...
The highly touted muscle-building benefits of methoxyflavone seem to be
a lot more hype than anything else, created for obvious reasons in the
process of trying to obtain patents. During the search for new
anabolics in the 1970's, researchers strived to develop a compound that
didn't have the pharmaceutical steroid status. The patent for
methoxyflavone (U.S. patent 4,163,746) was first filed in 1977 by
Chinoin, a Hungarian pharmaceutical company and leader in flavonoid
research and knowledge.

The research was aimed at finding a nutrient-repartitioning agent able
to transport much-needed nutrients away from fat tissue and toward
muscle tissue. Nothing much came of it, and the compound was shelved
for years. Then, in the 1980's, livestock producers introduced it as a
new compound to increase lean mass in animals. Now, some 20 years
later, with the end of its patent protection (which means anyone can
copy the product, which is easy, since patents have to list exact
manufacturing techniques), a new supplement, called methoxyisoflavone,
popped onto the performance-supplement market... with no real science
to back its claims.

Unfortunately, patents don't mean a product works. They just mean the
product is patented. In addition, methoxyflavones appear to have
negative effects on important testosterone-conversion enzymes, whereby
it inhibits the enzyme responsible for converting precursor hormones
into testosterone. And, due to its similar structure to ipriflavone, it
may even enhance the effects of estrogen in certain parts of the body
(which isn't in the least bit beneficial for men trying to put on
muscle mass).

What did the research say - for muscle building?
Research on methoxyflavones was originally conducted in the late 1970's
(yes, as in some 20 plus years ago) and found that when methoxyflavone
was given to rats, rabbits, and other barnyard animals, a small gain in
bodyweight of 10%% to 20%% was seen. It has also been tested on
emaciated, chronically ill patients and caused a gain of a few
kilograms of weight. This, today, is what the main marketing claims for
methoxy appear to be based on.

5-Methyl-7-methoxy-isoflavone patent research also shows that when the
isoflavone is methylated, it becomes more anabolic compared to
ipriflavone. This again gave marketers the idea to use substantiated
ipriflavone research in their claims.

Although this research is a bit dated, it suggests, to a limited
extent, that something was happening to body mass. From there, it was
presumed that either catabolism (muscle wasting) had been diminished or
some type of anabolic (muscle-building) action had taken place. Neither
has been determined to be the effective mechanism nor documented by any
conclusive studies. And the fact that there were no changes in hormone
levels, except partially suppressed cortisol levels, suggested that at
most, methoxyisoflavone may be a potential anti-catabolic agent
(meaning it may prevent muscle breakdown).

In conclusion
Methoxy has basically no conclusive research, and its anabolic benefits
are dubious and unfounded at best. Even so, livestock producers are
using it to naturally increase the size of their animals (hormone
free), so there's probably some potential here. And any potential
muscle-building effects of these supplements seems to occur as the
result of increased calcium, potassium, and nitrogen retention, as well
as by suppression of cortisol without androgenic or liver-damaging
effects.

All in all, if you're willing to roll the dice on a supplement that has
more hearsay than anything else and spend the money (it's pretty
expensive), methoxy might be worth a try for muscle support. But we'll
wait for more valid research before we draw our conclusions on its real
benefits.

NOTES ON USAGE

Amount and Timing
Most manufacturers' suggested range of 5-methyl-7-methoxy-isoflavone is
anywhere between 400 and 800 mg taken in 2 divided doses (200 to 400 mg
twice daily).

Note
Part of the problem with methoxyflavone is that it becomes inert
quickly, has a short half-life, and is destroyed in the stomach before
it reaches the liver. Studies used injections, not oral delivery, but
injection is considered a medical use and is thus illegal. And forget
about protein powders claimed to contain it. If they do have any, it
will be destroyed in the stomach before it enters the bloodstream.
Sublingual products in a liposome delivery system appear to be the
ideal form, but again this needs to be substantiated with independent
studies.

Synergists of Methoxyisoflavone
Ecdysterone allegedly increases protein synthesis along with methoxy,
but ecdysterone is also a questionable supplement.

Toxicity of Methoxyisoflavone
No known toxicity.

Bans and restrictions
None reported.

RELATED RESEARCH

Research on methoxy is almost nonexistent. Most of the research used by
manufacturers to support methoxy is actually for other isoflavones,
such as ipriflavone.

US Patent #4163746

US Patent #3949085

Incledon, T., et al., "The Effects of 5-Methyl-7-Methoxyisoflavone on
Body Composition and Performance in College-Aged Men," Human
Performance Specialists, Inc., Plantation, FL, and University of
Nebraska-Kearney, Kearney, NE. (Sponsor: Jose Antonio, FACSM).
Unpublished.

On Jan 25, 10:42 pm, "CoreyWhite" gmail.com> wrote: