http://pubs.nrc-cnrc.gc.ca/cgi-bin/rp/rp2_abst_e?cjc_v05-134_83_ns_nf_cjc

"A mild and efficient procedure for the conversion of aromatic
carboxylic esters to secondary amides.

A mild and efficient procedure has been developed for the conversion of
aromatic carboxylic esters to secondary amides using reusable Zn dust
with microwave heating in the presence of N,N-dimethylformamide or
conventional heating by stirring in an oil bath using THF as solvent.
Zn dust can be reused several times after simple washing with dil. HCl
and distilled water."

The dmf probably can be substituted with another base like imidazole or
triethylamine (just a guess) ...

Thilo wrote:

Yeah the Kolbe reaction:

http://designer-drug.com/pte/12.162.180.114/dcd/chemistry/electro-amph.txt

"Okay this synthesis involves the decarboxylation and methylation of
phenylalanine in one step. The basic equation is:

C6H5-CH2-CHNH3-COOH + CH3COONa --{electroysis @ Pt anode}-->
C6H5-CH2-CHNH2-CH3 + H2 + CO2

Library of Congress # QD273.F78, page 273

Wouldn't they just use phenylalanine?

Reply

nd Sorry will correct and expand tommorrow; I was stresssed. I keep
trying to talk someone into trying the Kobe; anyone have a current
variable battery charger; I had a gooid post but hit ESC and the
prision library is closing in 5 min. and I feel the same about
Fester;

Also - some of it is to hide in the lingo suzy begat tina; and eppie
begat tina also; Nicht Whar?

and at least it is in english; try using the deutsch patent on
amphetimines as a workbook!